Custom ASO Assay Development

Custom ASO Assay Development

Unlock Precision ASO Testing with Nucleic Acid Nanorobotics (NANs)

At Nanovery, we specialise in creating bespoke nucleic acid assays tailored to your
research needs using cutting-edge Nucleic Acid Nanorobotics (NANs). Our process
is designed to ensure precision and customisation from the ground up.

1
Initial Request and Defining Assay Needs
2
Assay Development
3
Evaluation Licence
4
Commercial Licence
Step 1

Initial Request and Defining Assay Needs

Get Started with Just the Basics:

To kick off your custom assay, we require just two essential pieces of information:

  • ASO Sequence
  • Chemical Modifications

These details enable us to use our sophisticated computational pipeline to start designing an assay that is uniquely yours. Secondary details such as concentration range and sample type can be adjusted and optimised subsequently, allowing us to focus on what really matters: your specific assay requirements. Schedule a consultation to discuss your needs in detail and learn more about our technology.

From First Contact to Validated Assay in Just 30 Days

We understand the importance of time in scientific research and development programmes. That’s why we’ve streamlined our process to deliver fully validated custom assays within 30 days of your initial contact. Our dedicated team works closely with you to ensure quick turnaround without compromising on precision or quality.

Speak with our ASO Specialist
Step 2

Assay Development

Rapid and Rigorous Development Process:

  • Initial Check (instant): Our automated system quickly determines the feasibility of developing a NAN for your ASO.
  • Design (1-5 days): We use a state-of-the-art computational pipeline to create NANs optimised for your specific needs. The design process varies in duration depending on the complexity of your ASO’s sequence and modifications.
  • Oligo Order (2-3 weeks): To ensure the highest standard of assay development, high-quality components are sourced from reputable third-party providers.
  • Assembly and Validation (1 week): The NANs are assembled and rigorously validated in our lab to confirm their accuracy and sensitivity.

Assay Development Pricing:

Each nanorobot we develop is tailored to a specific target and optimised to work in your unique conditions. While the initial development cost may vary based on project specifics, the end result is a highly efficient assay at an attractive, modest price per reaction. Contact us today for a detailed quote tailored to your needs.

Step 3

Evaluation Licence

Receive a three-month evaluation license with your assay development. This package comes with detailed instructions and enough reagents for 1000 reactions, allowing comprehensive testing in your own lab environment. Validate the performance of the NANs with your samples, ensuring they meet your exact requirements.

Step 4

Commercial Licence

Once you are satisfied with the NANs' performance, we can discuss a full
commercial license tailored to your ongoing needs. Our simple, cost-effective
solutions are designed to scale with your bioanalysis needs and are supported by
continuous technical assistance.

Simple, Transparent, Effective:

Our approach is designed to be straightforward and customer-centric, ensuring that you receive assays tailored to your unique challenges and opportunities. Let us help you simplify your bioanalysis with cutting-edge, cost-effective solutions.

Speak with our ASO Specialist

Schedule a consultation to discuss your needs in detail.

Having these questions?

What information do I need to provide to start developing a custom assay?

The sequence of the Antisense Oligonucleotide (ASO) and its chemical modifications are essential for starting the assay development process. While additional details like concentration range and sample types are not necessary for the initial check, having this information upfront is beneficial. We understand that each customer has unique needs and challenges, and we are genuinely curious about the obstacles each project faces. Our approachable and adaptable team tackles these challenges head-on. The more information you share with us about your specific requirements and hurdles, the better we can design and develop NANs to solve your problems effectively. We're resourceful and dedicated, striving to prove that our NANs work to address your unique challenges right from the very first experiment.

How long does the entire assay development process take?

What happens if my ASO sequence or modifications are something you haven’t worked with before?

How is the pricing determined for assay development and commercial licenses?

Accelerate your RNA Therapeutic Development with Precision Bioanalysis

At Nanovery, we harness the power of DNA Nanorobotics to advance RNA therapeutic research and development. Our custom assays are meticulously designed to help you reach patients faster and ensure your antisense oligonucleotides (ASOs) are developed to the highest standards of precision and efficacy.

Ready to transform your analytical processes? Join us at the forefront of biotechnological innovation to achieve results that matter.